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What is May-Thurner Syndrome?

May-Thurner syndrome, also known as iliac vein compression syndrome, is a condition where the left iliac vein in the pelvis is compressed by the overlying right iliac artery. This compression can lead to reduced blood flow in the vein, causing various symptoms and complications over time.

Side Effects of May-Thurner Syndrome

Patients with May-Thurner syndrome may experience a range of symptoms including:

  • Leg Swelling: Due to impaired blood flow, swelling (edema) in the left leg is common, especially after prolonged standing or sitting.
  • Pain and Discomfort: Persistent pain or aching in the left leg, often exacerbated by activities that increase venous pressure.
  • Varicose Veins: Visible veins that are swollen and twisted may appear on the left leg.
  • Skin Changes: Skin discoloration or ulcers may develop in severe cases, indicating compromised circulation.

How is May-Thurner Syndrome Diagnosed?

Diagnosing May-Thurner syndrome typically involves the following steps:

  • Medical History and Physical Examination: Your doctor will review your symptoms and conduct a physical examination, focusing on your legs and abdomen.
  • Imaging Tests: Ultrasound, computed tomography (CT) scan, magnetic resonance imaging (MRI), or venography may be used to visualize the affected vein and assess blood flow.

Potential Treatment of May-Thurner Syndrome

Treatment options for May-Thurner syndrome aim to relieve symptoms, improve blood flow, and prevent complications. These may include:

  • Anticoagulant Therapy: Blood-thinning medications (anticoagulants) may be prescribed to reduce the risk of blood clots forming in the affected vein.
  • Endovascular Procedures: Minimally invasive techniques such as balloon angioplasty and stent placement can be used to widen the compressed vein and restore normal blood flow.
  • Surgical Intervention: In rare cases or if other treatments are ineffective, surgery may be considered to remove the compressed portion of the vein or reroute blood flow.


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