What is Paget's Disease of Bone?
Paget's Disease of Bone is a chronic bone disorder characterized by abnormal bone remodeling. It typically affects older adults and leads to the formation of enlarged and weakened bones.
The exact cause is not fully understood, but it involves an imbalance in the normal bone remodeling process, where bone tissue is continuously broken down and replaced.
Side Effects of Paget's Disease of Bone
The most common symptoms include bone pain, deformities, fractures, and arthritis in the affected bones.
Due to the abnormal bone structure, patients may experience increased risk of hearing loss, nerve compression (such as spinal cord compression), and in rare cases, bone cancer.
How is Paget's Disease of Bone Diagnosed?
Diagnosis often involves a combination of clinical evaluation, imaging studies such as X-rays, bone scans, and blood tests to assess bone turnover markers.
Biopsy may be required in some cases to confirm the diagnosis and rule out other conditions.
Potential Treatments of Paget's Disease of Bone
Treatment aims to reduce symptoms, prevent complications, and normalize bone structure. Medications such as bisphosphonates are commonly used to slow down bone turnover and reduce the risk of fractures.
In some cases, surgery may be necessary to correct bone deformities or alleviate pressure on nerves.
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