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What is Sestamibi Scan?

A Sestamibi Scan, also known as a MIBI scan or a parathyroid scan, is a diagnostic procedure used to evaluate various conditions within the body, primarily focusing on the parathyroid glands, heart, and occasionally other organs.

The scan involves the injection of a small amount of a radioactive substance called technetium-99m sestamibi into a vein, which is then detected by a special camera that creates detailed images of the targeted areas.

It helps doctors identify abnormal tissue growth, blood flow irregularities, or functional abnormalities within the organs under investigation.

Side Effects of Sestamibi Scan

Generally, Sestamibi scans are considered safe with minimal risk of side effects. However, like any medical procedure involving a radioactive substance, there are a few potential considerations:

  • Allergic reactions: Although rare, some patients may experience allergic reactions to the radioactive tracer.
  • Radiation exposure: The amount of radiation used in a Sestamibi scan is low and typically considered safe. The benefits of the diagnostic information provided usually outweigh the risks associated with radiation exposure.

Patients who are pregnant or breastfeeding should inform their healthcare provider beforehand, as special precautions may be necessary to minimize any potential risks to the fetus or infant.

How is Sestamibi Scan Diagnosed?

The process of undergoing a Sestamibi scan is straightforward:

  • Injection: A small amount of technetium-99m sestamibi is injected into a vein, usually in the arm.
  • Waiting period: There is typically a waiting period of around 15-60 minutes, during which the tracer circulates and accumulates in the targeted organs or tissues.
  • Scanning: The patient lies on a scanning table while a gamma camera captures images of the distribution of the radioactive tracer. This helps in identifying areas of abnormality or dysfunction.

The entire procedure is conducted in a specialized nuclear medicine department under the supervision of trained healthcare professionals.

Potential Uses of Sestamibi Scan

The Sestamibi scan serves several diagnostic purposes:

  • Parathyroid gland evaluation: It is commonly used to locate abnormal parathyroid glands in cases of hyperparathyroidism.
  • Cardiac assessment: It can help assess blood flow and identify areas of reduced function or damage in the heart muscle.
  • Other organs: In some cases, the scan may be used to investigate abnormalities in other organs, such as the thyroid gland or certain types of tumors.


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