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Admin 11-28-2025 Cancer Treatments

Actinium-225 PSMA therapy for metastatic prostate cancer in Germany provides precise, advanced treatment led by Prof. Stefan Dresel. Learn about cost and patient care.

Actinium-225 PSMA Therapy: Revolutionizing Treatment for Metastatic Prostate Cancer in Germany

Metastatic prostate cancer in Germany, is an advanced stage of the disease in which cancer has spread beyond the prostate gland to distant organs such as the bones, lymph nodes, or liver. For patients facing this stage, conventional options like chemotherapy may offer limited results and can cause burdensome side effects. New targeted solutions are now transforming the treatment landscape, offering renewed hope and improved stability. Among these, Actinium-225 PSMA therapy for metastatic prostate cancer in Germany, stands out as a promising development, especially for those with treatment-resistant cancer.

Germany has become a global hub for this advanced therapy. With access to highly experienced specialists such as Prof. Stefan Dresel, precision nuclear medicine, and individualized treatment protocols, patients can undergo effective and well-monitored therapy. 

What Is Actinium-225 PSMA Therapy and How It Works in Germany

Actinium-225 PSMA therapy in Germany, uses targeted radiation to eliminate prostate cancer cells with high precision. PSMA (Prostate-Specific Membrane Antigen) is a protein found on the surface of most prostate cancer cells. In this therapy, the radioactive isotope Actinium-225 is bound to a PSMA-targeting ligand. When injected, this radioligand binds to PSMA-expressing cancer cells and delivers a powerful alpha radiation dose directly to the tumor while sparing surrounding healthy tissue.

This approach is especially beneficial for patients who have exhausted traditional treatments such as androgen deprivation therapy or chemotherapy. The alpha particles released by Actinium-225 have a high energy level and short range, making them effective in destroying cancer cells while reducing systemic damage.

Why Germany Is a Top Choice for Actinium-225 Prostate Cancer Therapy

Germany is internationally recognized for its excellence in nuclear medicine, theranostics, and targeted oncology. German cancer centers offer:

  • Certified radiopharmaceutical laboratories
  • Precision diagnostics with PSMA PET/CT imaging
  • Personalized dosimetry and treatment planning
  • Access to ongoing clinical trials

Ideal Candidates for Actinium-225 Therapy in Germany

Patients who may benefit from this therapy include:

  • Those with metastatic prostate cancer that no longer responds to hormone therapy
  • Individuals with multiple metastases including bone or lymph node involvement
  • Patients who are ineligible or intolerant to chemotherapy
  • Men with a confirmed PSMA-positive tumor, verified by PET-CT

Each candidate is evaluated based on their cancer history, imaging results, blood markers (like PSA levels), and overall health.

Treatment Process for Actinium-225 Therapy in Germany

  • Initial Evaluation: A complete medical consultation with nuclear medicine specialists. This includes a review of imaging (PSMA PET/CT), PSA levels, renal function, and blood counts.
  • Treatment Planning: The dose of Actinium-225 is calculated based on tumor burden and the patient’s size and health.
  • Therapy Administration: The radioligand is infused intravenously. Most patients do not require hospitalization and can return to light activities the same day.
  • Post-Treatment Monitoring: Follow-up includes PSA tracking, imaging to assess tumor response, and evaluation of any side effects.

Benefits of Actinium-225 PSMA Therapy for Advanced Prostate Cancer

  • Precisely targets and destroys cancer cells
  • Less toxicity than conventional chemotherapy
  • Delays disease progression in resistant cases
  • May reduce tumor size and pain associated with metastases
  • Improves PSA levels and quality of life

Patients often report improved mobility, reduced pain, and stabilization of overall health. Mild side effects like dry mouth or fatigue may occur but are typically manageable.

Prof. Stefan Dresel: Leading Expert in PSMA Radioligand Therapy

Prof. Dr. Stefan Dresel in Germany is one of the foremost authorities in Actinium-225 and Lutetium-177 PSMA therapy in Germany, he leads a highly specialized nuclear medicine team offering comprehensive theranostic approaches for prostate cancer patients.

His expertise covers:

  • Personalized therapy protocols
  • Precision imaging and diagnostics
  • Dosimetry optimization
  • Research in improving therapeutic efficacy

Patients from all over the world consult with Prof. Dresel due to his patient-centered approach and significant experience in metastatic prostate cancer treatment in Germany.

Cost of Actinium-225 PSMA Therapy in Germany

The cost of Actinium-225 therapy in Germany ranges between €18,000 and €20,000 per cycle. This generally includes:

  • Consultation with nuclear medicine experts
  • Imaging (PSMA PET/CT)
  • Laboratory testing and monitoring
  • Radiopharmaceutical production and drug infusion
  • Follow-up evaluation after therapy

TIG (Treatment in Germany) at www.treatmentingermany.de helps international patients coordinate the entire treatment and help with complete logistical support throughout their journey.

Clinical Trials and Research in Actinium-225 Therapy in Germany

Germany is one of the most active countries in clinical research for prostate cancer, especially Actinium-225-based therapies. Trials are currently testing:

  • Combination of Actinium-225 with immunotherapy or checkpoint inhibitors
  • Enhanced delivery systems and improved targeting ligands
  • Lower-dose strategies to reduce side effects

International Support for Patients Seeking Prostate Cancer Treatment in Germany

Germany welcomes patients from across UK, USA, Canada and Australia. Through TIG (Treatment in Germany) at www.treatmentingermany.de , international patients benefit from:

  • Bilingual coordination teams
  • Medical Visa ( if needed) and travel support
  • Appointments with top prostate cancer specialists
  • Follow-up care coordination

This makes the journey smooth and focused entirely on healing and comfort.



🌍Why Patients Worldwide Prefer Our Medical Services in Germany – Key Benefits Explained:


Frequently Asked Questions (FAQs)


What is Actinium-225 PSMA therapy?
It is a targeted treatment using radioactive Actinium-225 to destroy PSMA-positive prostate cancer cells.


Who is eligible for Actinium-225 therapy in Germany?
Patients with metastatic, treatment-resistant, or hormone-refractory prostate cancer and confirmed PSMA expression.


What are the main side effects of Actinium-225 PSMA therapy?
Mild dry mouth, fatigue, or low blood counts, which are usually temporary.


What makes Germany a leader in PSMA therapy?
Experienced doctors, advanced imaging, certified facilities, and ongoing research trials.


What is the cost of Actinium-225 therapy in Germany?
Between €18,000 and €20,000 per session, including diagnostics and monitoring.


How safe is Actinium-225 for my body?
It targets cancer cells directly, so healthy tissue is mostly spared and side effects are usually mild.


Are clinical trials for Actinium-225 therapy available in Germany?
Yes, German oncology centers explore combination therapies and new indications.


Can Actinium-225 therapy prevent cancer recurrence?
Targeted alpha therapy reduces recurrence risk by destroying metastatic cells.


Can Actinium-225 therapy treatment replace chemotherapy?
Yes, in some cases it’s used when chemotherapy fails or is not tolerated.


Who is the leading doctor for Actinium-225 PSMA therapy in Germany?
Prof. Dr. Stefan Dresel, an expert in nuclear medicine and theranostics.


How do I get a consultation in Germany?
Contact TIG (Treatment in Germany) at www.treatmentingermany.de for appointment scheduling and medical guidance.



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